hrp0095p2-267 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Gonadal Dusfunction in Polytransfused Beta-Thalassemia Patients

Noumi Mustapha , Baghous Houssem , Keddari Malika , Belbouab Reda , Terrak Rachid , Boukari Rachida

Introduction: Β-thalassemia is a chronic hereditary hemolytic anemia characterized by a defect of synthesis of beta-globin chains, particularly common in the Mediterranean region, southern Asia, and the Middle East. Chelation therapy significantly prolonged the life expectancy of patients. This has led to an increase in the prevalence of endocrine complications, linked to iron overload. Gonadal Dusfunction is a frequent complication in polytransfused beta...